china tr 52 titanium dioxide

Mexican researchers sought to evaluate the effects of E171 across a span of conditions in mice, including its influence on behavior, along with the effects on the colon and liver. The research, published in 2020 in the journal Food and Chemical Toxicology, showed that E171 promoted anxiety and induced adenomas, or noncancerous tumors, in the colon. They also found that E171 heightened goblet cells hypertrophy and hyperplasia, which is typically seen in asthma patients and triggered by smoking or external pollutants and toxins. They also noted mucins overexpression in the mice, which can be linked to cancer cell formation. 

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One of the key challenges facing the wholesale TiO2 market is the volatility in raw material prices, particularly for titanium-bearing ores such as ilmenite and rutile. These raw materials are subject to price fluctuations due to factors such as geopolitical tensions, supply chain disruptions, and changes in demand from end-use industries. As a result, manufacturers may face challenges in managing their production costs and maintaining competitive pricing in the market.

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